Boston University’ 26 | Researcher in Biostatistics & Computational Methods

Email: titigao [at] bu [dot] edu
GitHub: TianyiGao616
LinkedIn: tianyi-gao

About

I’m a recent graduate from Boston University, where I received a B.A. in Mathematics and Computer Science. My research interests boardly lies in applying statistics and computational knowledge to address health problems, especially those related to complex diseases. I plan for graduate school in biostatistics, and I hope to explore causal inference, longitudinal methods, and machine learning approaches for analyzing high-dimensional datasets. For more information, please refer to my CV.

Research Interests

  • Causal inference and mediation analysis
  • Statistical genetics and genomics
  • Longitudinal and time-to-event modeling
  • Machine learning and deep learning for electronic health data and biomedical applications

Research Experience

Below are selected research projects I have worked on:

Boston University, Department of Biostatistics

  • Research Assistant, with Ningyuan Wang and Prof. Ching-Ti Liu (2025–Present)
    • Working on high-dimensional heterogeneous mediation analysis methods
    • Implemented large-scale simulation studies using HPC on BU SCC and computed error metrics to evaluate the performance of different mediation methods
    • Contributing to the development of an R package for the mediation method
    • Currently transferring large-scale datasets to BU SCC for future analyses

Boston University, Department of Mathematics and Statistics

  • Independent Researcher for Undergraduate Honors Thesis, with Dr. Matthew Moore (2025)
    • Modeled ecological and epidemiological systems using ODE-based predator–prey models
    • Extended the classical two-species Lotka–Volterra model to a general n-species framework
    • Incorporated logistic growth terms and analyzed the resulting dynamical system
    • Performed stability and phase-plane analysis of the generalized models
    • Estimated model coefficients using three regression methods and evaluated estimation accuracy using statistical metrics

Boston University, Department of Mathematics and Statistics

  • Research Assistant, with Prof. Mark Kon (2025)
    • Built an ensemble machine learning pipeline for cancer classification using high-dimensional gene expression data (500 samples, 30k genes).
    • Applied SVM as base learners and Random Forest, Decision Tree, and Logistic Regression models as metalearners to identify biologically meaningful gene pathways.
    • Achieved 95% accuracy and extracted top 10–20 genes per meta-learner for biological interpretation.
    • Project code available on GitHub: Repository Link.

Teaching and Mentoring

I am passionate about teaching and enjoy helping students learn and grow. I worked as a Teaching Assistant for Analysis of Variance (MA 416) in Fall 2025. Starting in Fall 2022, I tutored middle and high school students in China in AP Calculus and the TOEFL exam. I also worked as a Peer Mentor at CAS, where I supported first-year students by offering academic guidance and advice on course planning and university life.

Presentations and Conferences

  • Presented my honors thesis, “Modeling Ecological and Epidemiological Systems Using Predator–Prey Dynamics”, at the Undergraduate Research Opportunities Program (UROP) Symposium, Fall 2025.
  • Successfully defended my undergraduate honors thesis before the Department of Mathematics faculty committee in December 2025.